Regulatory Science Tools Catalog
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
This regulatory science tool is a method and phantom design for the evaluation of iodine-specific quantitative measurements, specifically the accurate estimation of iodine concentration within contrast-enhanced spectral CT.
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
This regulatory science tool is a lab method that computes bone microstructure metrics to characterize bone morphology and skeletal geometry.
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
This regulatory science tool presents a set of tissue-mimicking phantoms suitable for benchtop performance assessment of photoacoustic imaging (PAI) devices.
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
The Virtual Imaging Clinical Trials for Regulatory Evaluation (VICTRE) computer modeling pipeline is a set of tools that allow for the replication of clinical trials of in silico breast radiographic images for the evaluation of digital mammography (DM) and digital breast tomosynthesis (DBT) devices.
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
The Virtual Family provides detailed three-dimensional computational models of the human anatomy including an adult male, an adult female, and two children
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
Test methods that provide a practical approach for objective, quantitative evaluation/comparison of fundamental performance in near-infrared fluorescence imagers.
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
A tool to generate computational scientific evidence as alternative approaches to clinical
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
Method to fabricate realistic microcalcification simulants with adjustable density and sizes, for insertion into phantoms used to evaluate x-ray breast imaging systems
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
MC-GPU is a Monte Carlo simulation code that can generate synthetic radiographic images and computed tomography (CT) scans of realistic models of the human anatomy using fast Graphics Processing Unit (GPU) cards.
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
Tool for assessing image quality of advanced nonlinear CT image reconstruction and denoising products, including but not limited to statistical iterative, model-based iterative, and deep learning-based methods
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
A method to assess texture reproduction of camera-phone-based medical devices with a dead leaves target
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
Best practices for standardized performance testing of infrared thermographs intended for fever screening
![AI ML](/sites/default/files/styles/card_large_image/public/2024-01/AI-ML.jpg?h=16255f10&itok=Mm7ieYLf)
Statistical tools (java GUI and R package) to analyze, size, and simulate multi-reader multi-case (MRMC) reader studies
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
Digital model available on NIH's 3D Print Exchange site that can be used to fabricate tissue simulating phantoms with biomimetic vascular structures derived from a clinical image
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
A mathematically easy to understand and experimentally simple method to quantitatively and objectively evaluate endoscope geometric distortion
![MID](/sites/default/files/styles/card_large_image/public/2024-01/MID.jpg?h=4f4ef907&itok=creHJZ75)
A software program written in Matlab for analyzing color performance testing data in endoscopy devices